Go slow with novices and first encounters to bondage. Be especially sensitive to your partner's emotional reactions, providing frequent gentle body contact, spoken encouragement and other reassurances.
BDSM Safety II.
Respect the limits of your partner at all times and use a bondage "safe word." Set up a safe word before you start to ensure that each participant can end his/her participation with a word or gesture.
BDSM Safety III.
Bondage should always be safe, sane and consensual between the partners. As long as you keep some basic safety precautions in mind you'll be able to enjoy bondage play without hurting anyone.